a tuberculinodiagnosis at children sick of a tuberculosis, sochetannym with a HIV-infection
Sensitivity to a tuberculin on a Mantoux reaction with 2 THOSE PPD-L at deyotej investigated groups is presented in table 4.13. In 1 group data about tuyoberkulinovyh assays were available for 108 children who have entered into working out for studying of character of sensitivity to a tuberculin.
The analysis of results has shown, that tuberkulinovaja assay with 2 THOSE plays less significant role in revealing and diagnostics of a tuberculosis at children, bolyonyh a HIV-infection, than at children without a HIV-infection, including with perinayotalnym contact on a HIV-infection.
Table 4.13 Sensitivity to a tuberculin at children of investigated groups on a Mantoux reaction with 2 THOSE PPD-L (n=300)
| Groups of children | Sensitivity to a tuberculin at the moment of disease revealing | In total children | |||||||||
| The negative | The doubtful | 5-14 mm | (normergich.) | 15-16 mm | (Expressed) | giperergicheskaja | |||||
| abs. | % | abs. | % | abs. | % | abs. | % | abs. | % | ||
| 1 | 38 | 35,2 | 2 | 1,8 | 50 | 46,3 | 10 | 9,3 | 8 | 7,4 | 108 |
| 2 | 1 | 1,0 | 5 | 5,2 | 44 | 45,4 | 23 | 23,7 | 24 | 24,7 | 97 |
| 3 | 1 | 1,0 | 6 | 6,3 | 55 | 58 | 16 | 16,7 | 17 | 18 | 95 |
| Total | 40 | 13,3 | 13 | 4,4 | 149 | 49,7 | 49 | 16,3 | 49 | 16,3 | 300 |
At the moment of tuberculosis revealing negative tuberkulinovaja assay was registered at every third in 1 group and practically otsutyostvovala in 2 and 3 groups. A share of children with negative reaction to assay
Mantu has made 35,2 % in 1 group and 1 % (on one child) cases in 2 and 3 groups (OSH = 53,5; Dee 39,6-72,8).
Doubtful reactions practically did not become perceptible in the basic group (at 2 of 108 children) and is rare in control groups (at 5 and at 6 children sootvetstyovenno). At children with a HIV-infection (1 group) expressed and giperergicheskie reactions to a tuberculin became perceptible in 2,9 less often, than at children of 2 groups and in 2,1 times - than at children of 3 groups (16,7 %, 48,4, 34,7 %; OSH = 0,21; Dee 0,1-0,4). RazYOnitsa between 2 and 3 group it is doubtful (p> 0,05).
Thus, sensitivity to a tuberculin at children sick tuyoberkulezom, sochetannym with a HIV-infection, is less expressed, than at children without a HIV-infection and more often the negative.
Partly, this fact can explain so high share of children with socheyotannoj a pathology, taped on appealability.
In table 4.13.1 becoming infected and revealing terms zayobolevanija on tuberkulinovym are presented assays.
Table 4.13.1
Prescription of becoming infected MBT and revealings of disease at children of investigated groups
| Groups of children | Term of revealing of disease depending on prescription of a becoming infected | In total children | |||||||
| In a current - of year ("bend") | 1 2 years | 3-4года | 5 years | ||||||
| abs. | % | abs. | % | abs. | % | abs. | % | ||
| 1 group | 40 | 57,1 | 13 | 18,6 | 9 | 12,9 | 8 | 11,4 | 70 (100) |
| 2 group | 35 | 36,5 | 47 | 48,9 | 13 | 13, 6 | 1 | 1,0 | 96 (100) |
| 3 group | 32 | 34,0 | 38 | 40,4 | 12 | 12,8 | 12 | 12,8 | 94 (100) |
| Total | 107 | 41,2 | 98 | 37,6 | 34 | 13,1 | 21 | 8,1 | 260 (100) |
As a whole, the tuberculosis was more often taped at prescription of becoming infected MBT more than 1 year, the share taped sick of a tuberculosis against "virayozha" tuberkulinovyh assays has made less than half (41,2 %). Among infiyotsirovannyh MBT more than 1 year more often the tuberculosis was taped at prescription inyofitsirovanija 1-2 years - 37,6 % of cases (at prescription 3-4 years - 13,1 % and 5 and more years - 8,1 %).
At children of 1 group the tuberculosis was more often taped on the first year infitsiyorovanija (in the "bend" period) in comparison with children of 2 and 3 groups (57,1 %, 36,5 % and 34,0 %; х2=30,24; r
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Other medical related information a tuberculinodiagnosis at children sick of a tuberculosis, sochetannym with a HIV-infection:
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- a tuberculinodiagnosis at children sick of a tuberculosis, sochetannym with a HIV-infection
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