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THE TABLE OF CONTENTS

INTRODUCTION................................................................................................. 3

Chapter 1. The SYNDROME of Down (the LITERATURE REVIEW)

1.1 Characteristics of a syndrome, prevalence, genetics..................

9

1.2 Physical development of children with a syndrome of Down................................ 17

1.3 Structure of congenital developmental anomalies at a syndrome of Down...... 19

1.4 Structure assotsiirovannyh with a syndrome of Down of diseases.

Features of implication, diagnostic and therapeutic approaches 22

1.5Дерматоглифика at a syndrome of Down................................................. 37

Chapter 2. The GENERAL CLINICAL CHARACTERISTIC of PATIENTS And

RESEARCH METHODS................................................................. 40

Chapter 3. RESULTS of OWN RESEARCHES

3.1 Estimation of physical development of children with a syndrome of Down.

Pertsentilnye curves of growth, masses of a body and a head circle........... 47

3.2 Analysis of frequency, clinical implications, diagnostics and treatment

Congenital developmental anomalies at children with a syndrome of Down................... 53

3.3 Research assotsiirovannyh with a syndrome of Down of diseases. 62

3.4 Features of psychomotor and speech development of children with a syndrome

Down. Neurologic aspects............................................................. 73

3.5 Diagnostic possibilities of a dermatoglyphics.............................. 78

THE CONCLUSION........................................................................................ 83

CONCLUSIONS AND PRACTICAL REFERENCES........................... 100

THE LITERATURE LIST...................................................................... 103

THE APPENDIX...................................................................................... 119

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Scientific source Semenova Natalia Aleksandrovna. STATE OF HEALTH of CHILDREN With the SYNDROME of Down. The dissertation on competition of a scientific degree of the candidate of medical sciences. Moscow - 2013. 2013

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