THE TABLE OF CONTENTS
THE LIST OF REDUCTIONS AND DESIGNATIONS.......................................... 4
STATISTICS.......................................................... 5
INTRODUCTION........................................................................................................
6CHAPTER 1. LITERARY DATA ON EARLY REVEALING OF THE TUBERCULOSIS AT CHILDREN AND TEENAGERS........................................... 11
1.1. Features of a tuberculosis at children and teenagers on the modern
Stage................................................................................................................... 11
1.2. Features of a tuberculinodiagnosis on a Mantoux reaction 2ТЕ in sovremenyonyh conditions 16
1.3. Diaskintestjv to diagnostics of a tubercular infection.............................. 21
CHAPTER 2. THE CHARACTERISTIC OF THE SURVEYED PATIENTS AND APPLIED METHODS OF INSPECTION..................................... 31
2.1. A general characteristic of the surveyed groups of patients........................ 31
2.2. Obshcheklinichesky methods......................................................................... 32
2.3. Laboratory methods............................................................................... 32
2.4. Dermal allergological assays in early diagnostics of a tuberculosis....33
2.5. Immunologic methods of research of blood serum................... 34
2.6. Methods of processing of the received results........................................... 35
CHAPTER 3. OWN RESULTS............................................. 36
3.1. The characteristic of group with for the first time taped clinical forms
tuberuleza.......................................................................................................... 36
3.2. The characteristic of group of children with revealing positive takes
Tuberculosis micobacteria................................................................................ 50
3.3. The characteristic of group of children with conversion tuberkulinovyh assays........ 55
3.4. Risk factors of development of a tubercular infection............................... 58
3.5. A clinical example.............................................................................. 64
3.6. Immunologic researches in studied groups......................... 69
3.6.1. Features of system of the general immunity and stimulirovannoj production
IFN-y In group of healthy children......................................................................... 69
3.6.2. Features of system of the general immunity and stimulirovannoj production
IFN-y At children with local forms of a tuberculosis.......................................... 72
3.6.3. Features of system of the general immunity and stimulirovannoj production
IFN-y At children with conversion tuberkulinovyh assays........................................... 78
3.6.4. The comparative analysis of immunologic indicators on
To groups........................................................................................................ 81
3.6.5. Features of subpopulation structure and stimulirovannoj production IFN-y at children with negative and positive takes with
Diaskintestj.................................................................................................... 84
CHAPTER 4. DISCUSSION............................................................................ 90
ALGORITHM OF DIAGNOSTICS................................................................... 102
CONCLUSIONS....................................................................................................... 103
PRACTICAL REFERENCES..................................................... 104
THE LIST OF THE USED REFERENCES.... 106
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