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Dynamics of structure of an intestinal microflora against therapy according to feces crops on a dysbacteriosis

At the analysis of data of crops of a feces on a dysbacteriosis against therapy in a subgroup And depression of all kinds of is conditional-pathogenic flora (UPF) has been taped, but quantity Klebsiella pneumoniać and Staphylococcus aureus (p< has most considerably decreased; 0,05).

On other representatives of a microflora of authentic differences it is not taped. Dynamics of structure of an intestinal microflora, according to feces crops on a dysbacteriosis, against therapy in a subgroup And is presented in table 59.

Table 59. Dynamics of structure of an intestinal microflora, according to feces crops on a dysbacteriosis, against therapy in a subgroup And

Microorganisms the Subgroup And (n=22) t d p
before treatment after treatment
Bifidobakterii 11,00±0,06 11,00±0,04 0,00 =1,00
Laktobakterii 7,00±0,07 6,90±0,09 0,88 =0,38
Citrobacter freundii 4,54±0,27 4,30±0,21 0,33 =0.74
Klebsiella oxytoca 5,31±0,42 4,72±0,30 1,60 =0,12
Klebsiella pneumoniae 5,13±0,33 4.72±0,22 2,41 =0,02
Staphylococcus aureus 4,36±0,12 3,80±0,24 2,86 =0,01

At the analysis of data of crops of a feces on a dysbacteriosis after course of treatment in a subgroup depression of all kinds UPF Would be observed: Citrobacter freundii, Klebsiella oxytoca and Staphylococcus aureus, but quantity Klebsiella pneumoniać (p< has authentically decreased only; 0,05). On other representatives of a microflora of authentic differences it is not taped. Dynamics of structure of an intestinal microflora, according to feces crops on a dysbacteriosis, against therapy in a subgroup is presented in table 60.

Table 60. Dynamics of structure of an intestinal microflora, according to feces crops on a dysbacteriosis, against therapy in a subgroup

Microorganisms

the Subgroup (n=20)

t d

p

before treatment after treatment
Bifidobakterii 10.80±0,20 9,95±0.49 1,63 =0,11
Laktobakterii 6,85±0,15 6,95±0,05 0,62 =0,54
Citrobacter freundii 4,00±0,02 3,99±0,01 0,45 =0,66
Klebsiella oxytoca 4,00±0,11 4,50±0,28 1,66 =0,10
Klebsiella pneumoniae 6,15±0,34 5,05±0,27 3,10 =0,007
Staphylococcus aureus 3,25±0,61 4,33±0,27 1,21 =0.24

At the analysis of data of crops of a feces on a dysbacteriosis against therapy in a subgroup In the tendency to depression of quantity Klebsiella oxytoca and Klebsiella pneumoniać and authentic depression of quantity Citrobacter freundii (p< has been taped; 0,05).

Authentic rising of quantity Staphylococcus aureus against reception of admixture NAN Comfort is taped. On other representatives of a microflora of authentic differences it is not taped. Dynamics of structure of an intestinal microflora, according to feces crops on a dysbacteriosis, against therapy in a subgroup In is presented in table 61.

Table 61. Dynamics of structure of an intestinal microflora, by results of feces crops on a dysbacteriosis, in a subgroup In against therapy

Microorganisms

the Subgroup In (n=20)

t d

p

before treatment after treatment
Bifidobakterii 10,45±0,22 9,70±0.35 1,59 =0,12
Laktobakterii 6,45±0,19 6,35±0,23 0,28 =0.77
Citrobacter freundii 4,95±0,35 4,05±0,05 2,16 =0,04
Klebsiella oxytoca 4,95±0,95 4,21±0,16 1,56 =0,13
Klebsiella pneumoniae 4,90±0,39 4,68±0,35 0,55 =0,58
Staphylococcus aureus 2,65±0,52 5,18±0,48 2,67 =0,023

Thus, according to feces crops on a dysbacteriosis as against correction by enzyme Lactase Bebi, and probioticheskoj therapies, depression of growth UPF, first of all Klebsiella pneumoniać and Staphylococcus aureus (subgroups as a whole became perceptible And. In a subgroup In depression of quantity Citrobacter freundii is noted also.

Authentic rising of quantity Staphylococcus aureus against reception of admixture NAN the Comfort, probably, reflects astable character of an intestinal biocenosis at children with FR in artificial feeding that is appreciably caused by absence of protective factors of female milk. However, as rising Staphylococcus aureus was not accompanied by intensifying of clinical implications FR, it is impossible to consider this separately taken microbiological indicator defining.

Dynamics of structure of an intestinal microflora against therapy according to PTSR a feces

At the analysis of data PTSR of a feces against therapy in a subgroup And the tendency to rising of quantity of representatives of an obligate intestinal microflora has been taped: bifidobaktery, laktobaktery, and also Bacteroides fragilis. Authentic depression of quantity Clostridium difficile (p< is taped; 0,05). The tendency to depression of quantity Klebsiella pneumoniać became perceptible. On the rests

to representatives of a microflora of authentic differences it is not taped. Dynamics of structure of a microflora, by results of PTSR a feces, against therapy in a subgroup And is presented in table 62.

Table 62. Dynamics of structure of an intestinal microflora, by results of PTSR a feces, in a subgroup And against therapy

Microorganisms the Subgroup And (n=22) t p
before treatment after treatment
Total of microbes 10,00±0,16 10,06±0,15 0,31 =0,76
Bifidobakterii 8,48±0,26 8.68±0,24 0,52 =0,60
Laktobakterii 5,83±0,44 6,10±0,34 0,47 =0,64
Bacteroides fragilis 8,45±0,31 8,54±0,25 0,24 =0,81
Clostridium difficile 4,38±0.41 3,19±0,19 3,12 =0,005
Enterococcus spp. 5,18±0,08 5,18±0,08 0,00 =1,00
Klebsiella pneumoniae 4,69±0,28 4,25±0,18 1,73 =0,09
Faecalibacterium prausnitzii 4.37±0,56 5,39±0,61 1,29 =0,21

d

At the analysis of data PTSR of a feces against therapy in a subgroup authentic depression of quantity Klebsiella pneumoniae (p< Would be taped; 0,05). The tendency to quantity rising laktobaktery, to depression of quantity Enterococcus spp is noted. And Clostridium difficile. On other representatives of a microflora of authentic differences it is not taped. Dynamics of structure of a microflora, by results of PTSR a feces, against therapy in a subgroup is presented in table 63.

Table 63. Dynamics of structure of an intestinal microflora, by results of PTSR a feces, against therapy in a subgroup

Microorganisms the Subgroup (n=20) t p
before treatment after treatment
Total of microbes 10,10±0,15 9,84±0,16 1,30 =0,20
Bifidobakterii 8,72±0,26 8,71±0,18 0,02 =0,92
Laktobakterii 5,88±0,49 6,19±0,43 0,48 =0,64
Bacteroides fragilis 8,98±0,27 8,32±0,41 1,67 =0,11
Clostridium difficile 3,73±0,34 3,12±0,12 1,93 =0,06
Enterococcus spp. 5,35±0,10 5,25±0,09 1,45 =0,16
Klebsiella pneumoniae 4,85±0,12 4,07±0,25 2,81 =0,008
Faecalibacterium prausnitzii 5,50±0,71 4,60±0,56 1,11 =0,28

d

At the analysis of data PTSR of a feces against therapy in a subgroup In authentic depression of total of microbes (p< has been taped; 0,05). On other representatives of a microflora of authentic differences it is not taped. Dynamics of structure of a microflora, by results of PTSR a feces, against therapy in a subgroup In is presented in table 64.

Table 64. Dynamics of structure of an intestinal microflora, by results of PTSR a feces, against therapy in a subgroup In

Microorganisms

the Subgroup In (n=20)

t d

p

before treatment after treatment
Total of microbes 10,20±0,14 9,66±0,16 2,93 =0,008
Bifidobakterii 8,96±0,18 8,63±0,18 1,77 =0,09
Laktobakterii 6,74±0,59 7,03±0,61 0,40 =0,68
Bacteroides fragilis 8,02±0,38 7,68±0,33 2,04 =0,06
Clostridium difficile 6,26±0,54 6,09±0,56 0,53 =0,60
Enterococcus spp. 6,13±0,13 6,00±0,06 0,91 =0,37
Klebsiella pneumoniae 4,00±0,02 3,97±0,04 0,67 =0,51
Faecalibacterium prausnitzii 3,00±0,25 3,36±0,36 0,82 =0,42

Thus, according to PTSR a feces against therapy quantity Clostridium difficile has decreased in a subgroup And, quantity Klebsiella pneumoniać Would decrease in a subgroup, the total of microbes has decreased in a subgroup of Century

Concluding the description of results of treatment FRZHKT at children of early age, it is necessary to underline necessity of the differentiated approach to a choice of tactics of therapy. At children with established LN on thoracal feeding appointment and #946 is optimum;-galaktozidazy (Lactases Bebi) which effectively eliminates clinical symptoms FR, hydrogen level in exhaled air reduces and promotes improvement of microbiological indicators of a feces.

Appointment probioticheskoj therapies L. reuteri to children with FRZHKT without LN also promoted cupping of clinical symptoms and improvement of microbiological indicators, first of all - to reduction UPF.

Improvement of microbiological indicators of a feces was accompanied by level depression kalprotektina in a feces, that indirectly testifies to depression of activity of an inflammation in an intestine and confirms its secondary character in reply to alteration of a microbiocenosis of an intestine.

Efficiency of treatment, by results of a mark estimation of expression FRZHKT, enzyme Lactase Bebi and probiotikom Rela Lajf, had no authentic differences (p> 0,05).

Shipping of enzyme Lactase Bebi, probiotika L. reuteri, both in the form of drops Rela Lajf, and as a part of admixture NAN Comfort, was good. At anybody from children it is noted allergic reactions, refusal of treatment and intensifying dispepsicheskih disorders. Against treatment at all children normal weight increases became perceptible.

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Scientific source KUBALOVA Saida Sultanovna. CLINICAL VALUE LAKTAZNOJ of INSUFFICIENCY And MICROBIC DISTURBANCES AT FUNCTIONAL DISORDERS of the GASTROENTERIC TRACT At CHILDREN of EARLY AGE. The dissertation on competition of a scientific degree of the candidate of medical sciences. St.-Petersburg - 2014. 2014

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Other medical related information Dynamics of structure of an intestinal microflora against therapy according to feces crops on a dysbacteriosis:

  1. dynamics of structure of an intestinal microflora against therapy according to feces crops on a dysbacteriosis
  2. INTRODUCTION
  3. THE TABLE OF CONTENTS
  4. Dynamics of structure of an intestinal microflora against therapy according to feces crops on a dysbacteriosis
  5. Chapter 7 DISCUSSION of RESULTS of RESEARCH