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CONCLUSIONS

1. Now prevalence of an anaemia in group of children, suffering chronic arthritises, makes 40,9 %. Prevalence and gravity of an anaemia appreciably depends on the form of a chronic arthritis, most often the anaemia complicates a current of the system form juvenilnogo a chronic arthritis.

2. Level gepsidina Serums assotsiirovan as with indicators of clinical and laboratory activity of a chronic arthritis (quantity of the joints involved in inflammatory process, an ESR, S-rb, quantity of leucocytes and thrombocytes), and with the indicators reflecting a metabolism of iron in an organism (concentration of a ferritin, level of soluble receptors of a transferrin, OZHSS and Serum iron).

3. Concentration of soluble receptors of a transferrin is the most significant indicator defining a dispersion of an average haemoglobin content in an erythrocyte which, in turn, is more sensitive indicator in forecasting of a current of an anaemia in comparison with the general concentration of haemoglobin.

4. Level gepsidina plasmas in a complex with other characteristics of an exchange of iron can be used for early differential diagnostics of an anaemia of chronic illnesses (including in a combination to deficiency of iron) and anemias in syndrome structure makrofagalnoj activation at children with chronic arthritises.

5. Blocking ИЛ-6 essentially changes dynamics of a current, both a chronic arthritis, and an anaemia accompanying it, and rate of cupping of an anaemia essentially above, than an arthritis. Blocking FNO - the alpha essentially accelerates cupping, both a chronic arthritis, and an anaemia, however terms of restoration of concentration of haemoglobin more than at blocking ИЛ-6.

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Scientific source EGOROV Andrey Sergeevich. THE GEPSIDIN-INTERLEUKIN-6 SYSTEM AS A FACTOR FOR MANAGING THE COURSE OF ANEMIA IN CHRONIC ARTHRITIS IN CHILDREN DISSERTATION for the degree of candidate of medical sciences. St. Petersburg - 2016. 2016

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