<<
>>

CHAPTER 4. DISCUSSION

Method of early revealing of a tuberculosis and becoming infected micobacteria of a tuberculosis children, still, have infectious character tuberkulinovoj to sensitivity on a Mantoux reaction 2ТЕ.

Last years to Russia according to order Minzdravsotsrazvitija Russian Federations N 855 "About modification of appendix N 4 to the order of Ministry of Health of Russia N 109", to the persons referred to antituberculous establishment for doobsledovanija on presence of tubercular process spend an intracutaneous test with preparation Diaskintestj.

The comparative characteristic of results of assay with preparation Diaskintestjs earlier known tuberkulinovymi assays at children with various forms of a tubercular infection is in a studying stage. This theme is actual now. A special problem soostavljajut data about presence of negative result Diaskintestjpri local forms of a tuberculosis and "bend" tuberkulinovoj Mantoux reactions with 2ТЕ in the presence of risk factors.

Studying of features of an immunodiagnosis at various implications of a tubercular infection in modern conditions was the purpose of our research.

Results tuberkulinovoj sensitivities on a Mantoux reaction 2 THOSE and assay with preparation Diaskintestju of children who have arrived on hospitalisation in children's antituberculous unit have been studied; antituberculous activity of immune system at children is studied; features of reaction of immune system are taped at local forms of a tuberculosis at children with negative result Diaskintestj.

We survey 145 children at the age from 1 till 17 years sick of a tuberculosis and children with "bend" tuberkulinovyh of assays and 85 children of corresponding age, not ill with a tuberculosis and not infected with tuberculosis micobacteria. At the first stage of work 2 groups are generated: group 1 - children with local forms of a tuberculosis - 100 children; group 2 - children with "bend" tuberkulinovyh assays - 45 children; and control group - 85 healthy children who have been not infected MBT (table 1).

All researches were spent according to the accepted report. According to the developed design of research studying of each of groups is spent and the comparative analysis between them is carried out. At the first stage the group with local forms of a tuberculosis is studied. In group of children with local forms of a tuberculosis tuberculosis forms are diagnosed: a tuberculosis of intrathoracic lymph nodes - 50 %, primary

Tubercular complex - 2 %; a focal tuberculosis - 15 %, infiltrativnyj a tuberculosis - 22 %, an exudative pleuritis of a tubercular aetiology - 6 %, vnelegochnyj a tuberculosis - 5 %. Among forms vnelegochnogo a tuberculosis - 2 cases of a tuberculosis of peripheric lymph nodes, 3 cases of a tuberculosis of bones.

Local forms of a tuberculosis were equally often taped at boys and girls, with small prevalence at boys. At comparison on age, most often the tuberculosis was taped at the age of 4-7 years (26 %) and is elderly 15­18 years (30 %). According to Jarovoj J.A., Korf G. V (2013г) in St.-Petersburg the maximum case rate at children became perceptible in 7 and 11 years. According to Nechaevoj O. B, (2013) for 2012 in the Russian Federation the maximum case rate was at children of 15-17 years.

At routine inspections disease is taped: during time

Mass tuberculinodiagnosis at 51 children, at the fluorographic
Inspection at 25 teenagers and at inspection of contact persons from the centre of a tuberculosis at 7 children.

Contact is a risk major factor at development of a tubercular infection; at the first reference contact is taped not always; at more careful studying of the epidemiological anamnesis in the course of observation over the child it was possible to come into contact with sick of a tuberculosis at 45 (45 %) patients.

At the reference with complaints from the general medical network 17 % (17) children are taped. The given indicator shows, that a tuberculinodiagnosis method, on - former, remains to leaders in revealing of a tuberculosis at children.

By results of a tuberculinodiagnosis it is taped, that on a Mantoux reaction with 2ТЕ and assay Diaskintestjbolshinstvo of children had the expressed positive takes of 10-16 mm - 62 % at a Mantoux reaction 2 THOSE and 31 % at assay Diaskintestj (r

<< | >>
Scientific source Ahmerova Tatyana Efimovna. IMMUNODIAGNOSIS OF DIFFERENT MANIFESTATIONS OF TUBERCULOSIS INFECTION IN CHILDREN. Thesis for the degree of candidate of medical sciences. SAMARA - 2014. 2014

Скачать оригинал источника
Помощь с написанием учебных работ

Other medical related information CHAPTER 4. DISCUSSION:

  1. CHAPTER 4. DISCUSSION
  2. Chapter 4 Discussion of the received results
  3. THE TABLE OF CONTENTS
  4. THE TABLE OF CONTENTS
  5. Chapter 7 DISCUSSION of RESULTS of RESEARCH
  6. the Maintenance:
  7. CHAPTER 8. THE CONCLUSION (DISCUSSION OF THE RECEIVED RESULTS)
  8. CHAPTER №5 DISCUSSION
  9. Chapter 5 Discussion of the received results
  10. THE TABLE OF CONTENTS
  11. Chapter 7 DISCUSSION of RESULTS of RESEARCH
  12. CHAPTER 4. THE CONCLUSION (DISCUSSION OF THE RECEIVED RESULTS)