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bacterination against a tuberculosis (BTSZH) and its efficiency at children born from women, sick HIV - an infection

Preventive inoculations against a tuberculosis are provided FeYOderalnym by the law from September, 17th, 1998 № 157-FZ About immunoprofiyolaktike infectious diseases, and now in the Russian Federation more than 95 % noyovorozhdennyh inoculate against a tuberculosis.

Till 2011 presence of a HIV-infection at mother was protivopokayozaniem for carrying out of antituberculous bacterination in a maternity home newborn [104, 105]. To vaccinate such children a vaccine of BTSZH TH it was supposed after achievement of age of 18 months when it was definitively possible to take out the HIV-infection diagnosis. Therefore vaccinated in royodilnom the house of children born from women, sick HIV-infections, it is casual in the absence of data on presence of a HIV-status at parturient women more often.

In our research from children sick of a tuberculosis, born from women with a HIV-infection, vaccinated by vaccine BTSZH or BTSZH TH has appeared 60 persons. As a part of children with a tuberculosis were sick of a HIV-infection, and a part of children were observed on perinatalnomu to contact with

HIV-infection (subsequently the HIV-infection diagnosis is not confirmed), for the analysis of clinical efficiency of vaccine BTSZH patients have been parted on 2 groups (table 7.6):

- Children, sick HIV-infections (on МКБ-10 - В23);

- Children with perinatalnym contact on a HIV-infection (on МКБ-10 - R75).

Table 7.6

Presence of bacterination btszh / by BTSZH TH at children sick of a tuberculosis

btszh / BTSZH TH Groups sick of a tuberculosis In total
В23 R75
abs. % abs. % abs. (%)
It is vaccinated 45 41 15 15,5 60 (29,1)
nevaktsinirovano 61 56,3 80 82,5 141 (68,5)
There are no data 3 2,7 2 2 5 (2,4)
In total 109* 100 97 100 206 (100)

*Примечание: from group of children sick of a tuberculosis, sochetannym with a HIV-infection (166 persons), data on bacterination or its absence and are not present data contained at 109детей.

As follows from table 7.6, are vaccinated BTSZH among patients tuyoberkulezom have appeared third (29,1 %) children. The share vaccinated among deyotej with a HIV-infection was much more (41 %), than among children with peyorinatalnym contact on a HIV-infection (15,5 %).

It is possible to assume, that the women which children were born by an infection from a HIV - were less often observed on pregnancy and is more often arrived in rodilyonoe unit without a HIV-status establishment, than the women who have given birth to children without a HIV-infection, therefore wrongly more often under bacterination got children with a HIV-infection. In most cases, predictably, children born from women with a HIV-infection have been vaccinated BTSZH, in conditions royodilnogo houses for 3-7 days of a life - their share has made 75 % from all vaktsiniyorovannyh (table 7.7).

Among children with a HIV-infection, vaccinated in
Maternity home, was a little bit more (80 %), than among children without a HIV-infection (60 %), that in any measure earlier come out assumption confirms.

Table 7.7

Terms of bacterination of children sick of a tuberculosis (n=60)

Age of the diseased Bacterination terms In total abs. (%)
The r/house abs. (%) Till 1 year abs. (%) 1-1,5 years abs. (%) 1,6-2 years abs. (%)
Years В23 n=45
0-2 12 (26,7) - - - 12 (26,7)
3-6 18 (40) 1 (2,2) 2 (4,4) 2 (4,4) 23 (51,1)
7-14 6 (13,3) 1 (2,2) 1 (2,2) 2 (4,4) 10 (22,2)
In total (n) 36 (80,0) 2 (4,4) 3 (6,7) 4 (8,9) 45 (100 %)
Years R75 n=15
0-2 3 (20) 2 - - 5 (33,3)
3-6 5 (33,3) 1 (6,7) 3 (20) - 9 (60)
7-14 1 (6,7) - - - 1 (6,7)
In total (n) 9 (60) 3 (20) 3 (20) 15 (100 %)
Total (n) abs., % 45 (75,0) 5 (8,3) 6 (10,0) 4 (6,7) 60 (100 %)

Other children (25 %) have been vaccinated in the conditions of a nursery poliyokliniki approximately in peer shares till 1 year (8,3 %), from 1 year till 1,5 years (10 %) and after 1,5 years (18 months) till 2th years (6,7 %).

Among vaccinated children the share sick of a tuberculosis was naiyobolshej at the age of 3-6 years: 51,1 % - in group V23 and 60 % - in group R75.

7.2.1.

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Scientific source KLEVNO HOPE IVANOVNA. TUBERCULOSIS At CHILDREN, SICK HIV-INFECTIONS (prevalence, features of clinical implications, diagnostics, treatment, preventive maintenance). The dissertation on competition of a scientific degree of the doctor of medical sciences. Moscow - 2015. 2015

Other medical related information bacterination against a tuberculosis (BTSZH) and its efficiency at children born from women, sick HIV - an infection:

  1. THE TABLE OF CONTENTS
  2. INTRODUCTION
  3. diagnostics of a tuberculosis at children with a HIV-infection
  4. absence of bacterination against a tuberculosis
  5. bacterination against a tuberculosis (BTSZH) and its efficiency at children born from women, sick HIV - an infection
  6. THE LITERATURE LIST