absence of bacterination against a tuberculosis

In the conditions of a wide circulation of a tubercular infection and znayochitelnogo burden of a tuberculosis (by an estimation the CART Russia is among the designated countries) one of the important preventive actions for depression of a case rate and a mortality from progressing forms tuberkuyo
leza, such as miliarnyj the tuberculosis, a meningitis, at children is vaktsinayotsija against a tuberculosis (vaccine BCG).

Many authors absence of bacterination against tuyoberkuleza, especially at children of early age becomes perceptible, that, raises risk of development zaboyolevanija, including with its occurrence generalizirovannyh forms [71,72,73 180, 193].

Presence of antituberculous bacterination at children sick tuberkuyolezom investigated groups is presented in table 7.1.

Table 7.1

Presence of bacterination BCG at children from observation groups (n=358)

btszh / BTSZH TH Groups of patients
1 group 2 group 3 g ruppa
abs % abs % abs. %
It is vaccinated 45 41,3 15 15,5 93 98
nevaktsinirovano 61 56,0 80 82,5 1 1
There are no data 3 2,7 2 2 1 1
In total 109* 100 97 100 95 100

The note: 109* - at stolkih patients from the given group (166 children) data on bacterination against a tuberculosis are specified

As one would expect, in 3 group of patients practically all children have been vaccinated against a tuberculosis - in 98 % of cases. In 2 group bolyonyh their only small part - 15,5 %, in and 41,3 % - in 1 group of patients is vaccinated BTSZH. Absence of bacterination at the majority of children born from sick HIV-infections of women, speaks that on a national calendar of preventive inoculations till 2011 presence of a HIV - of an infection at the woman was contraindication for bacterination against a tuberculosis of newborns to 18 monthly age [104, 105]. For it vreyomja a part of children had time to be infected with tuberculosis micobacteria, a part of children were not observed in medical institutions and consequently did not receive vaccine BTSZH, and a part from them in the subsequent were ill with a tuberculosis. VakYO
tsinirovalis children in maternity homes casually as a HIV-infection at parturient women it was taped later.

In a dale of vaccinated children of 1 and 2 groups it is possible to explain a difference partly to that women with a HIV-infection which children have not caught a HIV, have socially been more adapted, were observed in profile meyoditsinskih establishments and during sorts their HIV-status was known.

As children, absence of bacterination BTSZH, probably were ill with a tuberculosis and vaccinated and nevaktsiniroyovannye, cannot be osyonovnym a risk factor of development of a tuberculosis at children, sick HIV - an infection that does not contradict literary data on researches of efficiency of bacterination BTSZH [130].

In the previous chapter it has been shown, that disseminirovannye processes, including miliarnyj a tuberculosis of plural localisation (generaliyozovannyj the tuberculosis), authentically met in 1группе patients - practically at every fifth sick HIV-infection (at 19,3 % against 4,1 % and 5,3 % in 2 group and 3 group accordingly) is more often.

Thus, in group of children who were born from women, sick HIV - an infection, practically under peer conditions of absence of bacterination BTSZH, in the basic group disseminirovannye and "generalised" processes pochyoti 10 times met more often on the basis of what it is possible to draw a conclusion, that a major factor of risk of development disseminirovannyh processes is not absence of bacterination against a tuberculosis, and the HIV-infection.

Besides, according to foreign publications, at children from a HIV - an infection bacterination BTSZH appears less effective on the zayoshchitnomu to action, than in usual population of children [180]. In more details our own observations by clinical efficiency and bezopasnoyosti vaccines BTSZH at children, sick HIV-infections, are stated more low.


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Scientific source KLEVNO HOPE IVANOVNA. TUBERCULOSIS At CHILDREN, SICK HIV-INFECTIONS (prevalence, features of clinical implications, diagnostics, treatment, preventive maintenance). The dissertation on competition of a scientific degree of the doctor of medical sciences. Moscow - 2015. 2015

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Other medical related information absence of bacterination against a tuberculosis:

  1. 4.1. Studying of a microbiocenosis of a stomatopharynx and an intestine in nasopharyngeal washouts and excrements
  3. clinical aspects of a tuberculosis, sochetannogo with a HIV-infection
  4. diagnostics of a tuberculosis at children with a HIV-infection
  5. 1.5.1. Bacterination
  6. 1.5.2. Preventive treatment of a latent tubercular infection (tuberculosis chemoprophylaxis) at children
  7. the characteristic of a clinical material
  8. features of a current of a tuberculosis, sochetannogo from a HIV - an infection, at early and late stages of a HIV-infection
  9. the Conclusion.
  10. terms of revealing of a HIV-infection and appointment art
  11. risk factors of disease by a tuberculosis of children from a HIV a-infection
  12. absence of bacterination against a tuberculosis
  13. bacterination against a tuberculosis (BTSZH) and its efficiency at children born from women, sick HIV - an infection
  14. Safety of bacterination BTSZH of children, sick HIV-infections.