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RESULTS OF TREATMENT OF PATIENTS WITH BISFOSFONATNYM THE OSTEONECROSIS OF JAWS

The first group of research «conservative treatment with application of local ozonotherapy» included 38 patients at the age from 32 till 78 years. Distribution of patients on a floor: 16 men (42,1 %) and 22 women (57,9 %).

The osteonecrosis centre was localised on the top jaw at 15 patients, on a mandible - at 20 patients, at 3 patients sites of an osteonecrosis both on top, and on a mandible have been taped.

Second group of research «conservative treatment» consisted of 22 patients at the age from 42 till 76 years by which conservative treatment of an osteonecrosis without ozonotherapy application was spent. The number of men made 7 persons (31,8 %), women - 15 persons (68,2 %). At 9 patients osteonecrosis localisation was on the top jaw, at 1 2 patients - on a mandible, at 1 patient osteonecrosis sites were defined on top and a mandible (Table 9).

After primary survey, carrying out of additional methods of research and statement of the definitive diagnosis to patients the advisory conclusion for the treating doctor-oncologist stood out. The treating doctor - the oncologist made the decision concerning possibility of cancellation of therapy bisfosfonatami, and also possibilities of carrying out of courses of ozonotherapy (for patients of the first group): at all patients therapy bisfosfonatami on a basis zolendronovoj acids has been cancelled or suspended for osteonecrosis treatment. For patients of the first group the permission to carrying out of treatment with application of local ozonotherapy is received.

Table 9

Distribution of patients on groups depending on localisation of osteonecrotic process

Localisation 1 group (with ozonotherapy) Abs., % 2группа (control)

Abs., %

The top jaw 11 (50 %) 15 (39,5 %)
Mandible 10 (45,5 %) 20 (52,6 %)
Top and bottom

Jaws

1 (4,5 %) 3 (7,9 %)

Before the beginning of treatment to patients of both groups suggested to fill the modified Poppy-Gillovsky a painful questionnaire which allows to estimate character and intensity of a pain (the Appendix 1). At carrying out of the analysis of results of questioning affective disorders have been taped both sensory, and.

The sensory characteristic of a pain. From the first 13 subscales which estimate the sensory characteristic of a pain (what words you can describe the pain?), 71,4 % of patients estimate the pain as aching, 40,5 % - pulling, 28,6 % - pressing, 27,2 % - described a pain as stupid, acute character of a pain was noted only by 15,3 % of patients.

The index of number chosen deskriptov (ICHVD) has made 6,14 0,6. The average estimation of a pain on rangovomu to a pain index (RIB) has made 9,8 0,9 points.

Affective scale of a pain. At the analysis chosen deskriptov in subscales 14-19 (What feelings the pain causes, what influence renders on mentality?) the majority of patients (72,5 %) have noted exhausting character of a pain, 43,2 % of patients describe a pain as weakening and irritating. 35,7 % - characterise the feelings as a pain-torture. The pain causes feeling of alarm in 20,3 % of patients.

The index of number chosen deskriptov at the surveyed patients has made 3,3 0,2, RIB - 8,14 0,8 points.

Evaljuativnaja a pain scale. Before the beginning of treatment the majority of patients estimated the pain as the strongest (41,7 %) and strong (45,0 %), only 13,3 % named a pain moderated. RIB has made 3,43 0,4 points.

For the purpose of an objective estimation of a condition of immune system to all patients the analysis of indicators of local and general immunity before the beginning of carrying out of treatment was carried out.

At carrying out of the analysis of indicators of the immune status at all surveyed patients depression of relative and absolute number T-limfotsitov and V-limfotsitov at the expense of all subpopulations (Table 10) is taped. Number T-helperov and T-supressorov is lowered in 1,23 times (r

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Scientific source ZASLAVSKAYA NATALIA ALEKSANDROVNA. OPTIMIZATION of PREVENTIVE MAINTENANCE And TREATMENT BISFOSFONATNYH of OSTEONECROSES of JAWS At PATIENTS WITH MALIGNANT NEOPLASMS. The dissertation on competition of a scientific degree of the candidate of medical sciences. Moscow - 2014. 2014

Other medical related information RESULTS OF TREATMENT OF PATIENTS WITH BISFOSFONATNYM THE OSTEONECROSIS OF JAWS:

  1. INTRODUCTION
  2. a pathogenesis, diagnostics, treatment bisfosfonatnogo an osteonecrosis of jaws
  3. RESULTS OF CLINICAL INSPECTION OF PATIENTS WITH BISFOSFONATNYM THE OSTEONECROSIS OF JAWS (1 AND 2 GROUPS OF PATIENTS)
  4. RESULTS OF RADIOLOGICAL INSPECTION OF PATIENTS WITH BISFOSFONATNYMTHE OSTEONECROSIS OF JAWS (1 AND 2 GROUPS OF PATIENTS)
  5. RESULTS OF TREATMENT OF PATIENTS WITH BISFOSFONATNYM THE OSTEONECROSIS OF JAWS
  6. CHAPTER 4. DISCUSSION OF RESULTS OF OWN RESEARCHES
  7. THE LITERATURE LIST