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CONCLUSIONS

1. The clinical picture bisfosfonatnogo an osteonecrosis is characterised by presence in an oral cavity is long not healing painless site of the bared osteal tissue of grey-yellow colour with a hilly surface, implication of the expressed inflammatory reaction of surrounding tissues and formation of fistulous courses on a skin thus is not characteristic.

2. Feature of a X-ray pattern bisfosfonatnogo an osteonecrosis of jaws is presence of areas of the raised density of an osteal tissue in zones of a formed necrosis (in 96,7 % of our observations), the expressed periosteal reaction in the field of the osteonecrotic centre is not characteristic.

3. The analysis of a histological picture and morphometry indicators testifies to secondary character of osteal sequesters in group sick bisfosfonatnym an osteonecrosis to what characteristics sekvestrirovannyh osteal fragments testify that specifies in aseptic and probably vascular genesis of process.

4. Ozonotherapy application in treatment bisfosfonatnogo an osteonecrosis leads to improvement of local immunity in an oral cavity (rising of activity and intensity of a phagocytosis in 1,2 and 1,67 times accordingly, and also rising of maintenance S-IgA in a saliva in 1,25 times), to reduction of expression of a painful syndrome at patients (depression of an index of a pain on a sensory and affective scale in 5,3 and 6,1 times accordingly is taped), and also to acceleration of formation of sequesters (r

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Scientific source ZASLAVSKAYA NATALIA ALEKSANDROVNA. OPTIMIZATION of PREVENTIVE MAINTENANCE And TREATMENT BISFOSFONATNYH of OSTEONECROSES of JAWS At PATIENTS WITH MALIGNANT NEOPLASMS. The dissertation on competition of a scientific degree of the candidate of medical sciences. Moscow - 2014. 2014

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