<<
>>

METHODS OF THE ASSESSMENT OF THE CELLULAR PART IMMUNE SJS'GEMY

Estimated a state cellular effektornogo an immunodefence part on following parametres:

To-absolute and relative number of lymphocytes in peripheric blood;

-otn'ositelnomu n to absolute quantity of mature T lymphocytes (CD3 and E-ROL);

To quantity teofillinrszistentnyh (TfR-limfotsity) and tsofillinchuvstvitelnyh (TfCh-limfotsity) T lymphocytes;

To-interrelation TFR/TFCH of lymphocytes on an immunoregulatory index;

-On an integrated indicator to a lenko-t-index;

Absolute and relative quantity of lymphocytes defined on lejkogramms. For identification of T lymphocytes (E-ROL) used well ‘ the established ability the sir-t-cellular of an antigen to co-operate with erythrocytes of the ram in reaction E-rozstkoobrazovanija (Petrov R. V, Hantov R. M, Pinegin B.V. with soavt., 1993; Leskov V. P with soavt., 1997).

Activity and expressiveness of the E-receptor defined on number of the lymphocytes of erythrocytes of the ram fixed on a surface (EB). Nizkoaktivnymi considered cages with adsorbed EB from 3 to 5, averages - from 6 to 8, highly active - from 9 and more.

On sensitivity of cages to teofillinu estimated function of membranes of 1-lymphocytes (Haitov R. M, Pinegin B.V., Istamov H.I 1995). For this purpose applied the loading test with teofillinom. Inkubatsija with this preparation leads to depressing E-rozetkoobrazovanija mainly the cages possessing supressornoj activity (teofillinrezistentnye - TFR) (Limatibui et al., 1978; MacDonald D.M., 1982; Kovalchuk A.V., Starikova S.J., 2003). Calculated integrated indicators:

Immunoregulatory index on an interrelation of TFR/TFCH-LYMPHOCYTES.

Lejko-t-index calculated under the formula: number of leucocytes / absolute quantity of T lymphocytes. The indicator from 7,0 to 9,0 testifies to presence immunodefitsitnogo states (IDS) I degrees, from 10 to 12 - II item, more than 12 — III degrees (Haitov R. M, 2001., Chereshnev V. A, Kevorkov N.N., Bahmetev B.A., 2001).

9

2.5.3

<< | >>
Scientific source RODIONOVA SVETLANA VIKTOROVNA. STUDYING of EFFICACYY of IMMUNOMODULATING FACTOR DERINATA In TREATMENT of CHRONIC JET ARTHRITISES HLAMIDIJNOJ of the ETIOLOGY At CHILDREN. The DISSERTATION on competition of a scientific degree of the candidate of medical sciences. Saransk 2007 . 2007

Other medical related information METHODS OF THE ASSESSMENT OF THE CELLULAR PART IMMUNE SJS'GEMY:

  1. features of system of the general immunity and stimulirovannoj production IFN-y in group of healthy children
  2. THE LIST OF THE USED REFERENCES
  3. forecasting of probability of conservation of effect of antiviral therapy at HG a method of the analysis of survival rate
  4. the Pathology of immune supervision as a basis of a pathogenesis of rheumatic diseases
  5. THE LITERATURE LIST
  6. modern methods of diagnostics of infectious diseases: detecting of microorganisms on the structural, genetically determined fat acids in object of research by means of a method of a gas chromatography of mass spectrometry
  7. CHAPTER 5. RESULTS OF STUDYING OF MICROORGANISMS ON THE STRUCTURAL, GENETICALLY DETERMINED FAT ACIDS IN OBJECT OF RESEARCH BY MEANS OF THE METHOD OF THE GAS CHROMATOGRAPHY OF MASS SPECTROMETRY
  8. studying of microorganisms on the structural, genetically determined fat acids in blood by means of a method of a gas chromatography of mass spectrometry
  9. THE CONCLUSION
  10. THE LITERATURE LIST
  11. THE LITERATURE LIST
  12. Chapter 1 the literature Review
  13. Chapter 2 Base, the program, a research technique
  14. methods of the statistical analysis of results of research
  15. THE CONCLUSION