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Conclusions

1. The maintenance rekombinantnogo human rekombinantnogo morphogenetic fiber of a bone rhBMP-2 as a part of an osteoplastic material on a basis nedemineralizovannogo an osteal matrix during research on biological model does not interfere with adhesion of cells - of precursors of fibroblasts on its surface.

2. According to a scanning submicroscopy a microrelief of a surface of an osteoplastic material in the form of granules with the sizes 700 800 microns on a basis nedemineralizovannogo an osteal matrix are optimum for adhesion of cells-predecessors of an osteal brain.

3. Presence rekombinantnogo human morphogenetic fiber of a bone rhBMP-2 as a part of an osteoplastic material on a basis nedemineralizovannogo an osteal matrix does not influence a wound process current in the postoperative period in relation to comparison group.

4. With the help gistromorfologicheskogo a research method better quality of a neogenic osteal tissue in defect of a calvaria of a rat in experimental group is established at defect filling nedemineralizovannym by the osteal matrix sated rekombinantnym with human morphogenetic fiber of a bone rhBMP-2 (2,3 points) in relation to comparison group at application pure nedemineralizovannogo an osteal matrix (2 points). Structurally issued osteal tissue is received at application rekombinantnogo human morphogenetic fiber of a bone rhBMP-2 in a complex with the carrier.

5. On the basis of results of a computer tomography of an authentic difference in the area of filling of defect to term 3 months between group of comparison and experimental group are not taped by a neogenic osteal tissue.

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Scientific source Doliner Michael Ellevich. Studying of osteoinductive activity of the osteoplastic materials containing rekombinantnyj morphogenetic fiber of a bone rhBMP-2, in experimental models. The dissertation on competition of a scientific degree of the candidate of medical sciences. Moscow - 2014. 2014

Other medical related information Conclusions:

  1. THE CONCLUSION
  2. THE CONCLUSION
  3. CONCLUSIONS
  4. THE CONCLUSION
  5. Conclusions of the first section
  6. 4.3 Conclusions of the fourth section
  7. Conclusions under chapter 1
  8. Conclusions under chapter 3
  9. CONCLUSIONS UNDER CHAPTER 1
  10. CONCLUSIONS UNDER CHAPTER 2
  11. Conclusions under Chapter 1
  12. Conclusions on the second chapter
  13. the Conclusion
  14. Conclusions under chapter 1
  15. Conclusions under chapter 2
  16. Conclusions under chapter 3